10/29/2023 0 Comments Definition synovial fluid![]() The main purpose of lubricin is to reduce the friction that would otherwise occur between the different cartilaginous surfaces. ![]() Lubricin is an essential component of the synovial fluid, being secreted by the fibroblasts of the synovial membrane and guaranteeing its lubricating properties. Keep in mind that the hyaluronic acid is produced by the cells of the synovial membrane and that it has different purposes: increased viscosity of the synovial fluid, better elasticity for the joint cartilage and lubrication of the articular surface, commonly found between the synovial membrane and the actual cartilage. ![]() In healthy people, this is the composition of the synovial fluid: hyaluronic acid, disaccharides and glucosamine. Apart from hyaluronic acid, the synovial fluid also contains other substances, such as lubricin (hence the lubrication properties), proteinases and collagenases. The second type – type B – are the cells that actually produce the synovial fluid. The first type – type A – refers to the cells that derive from monocytes (blood cells) these cells work to remove the debris that results from the wear and tear process, which occurs normally with aging (these are also known as phagocytic cells). It is composed from two main types of cells. It should be noted that the composition of the synovial fluid is 100% sterile, being primarily organized of connective tissue that is vascularized. ![]() The composition of the synovial fluid includes: hyaluronic acid, which is secreted by cells that resemble fibroblasts and which are part of the synovial membrane and interstitial fluid, the latter being filtered from the plasma. When a joint is moved, the synovial fluid is going to be used in order to ensure the lubrication of the respective joint (mechanical squeeze over the surface of the cartilage) Composition In a way, the synovial fluid found inside a joint is actually a reserve for the rest of the joints. Given the fact that the joint cartilage might present certain irregularities and small cavities, the synovial fluid will cover all of them, filling each empty space inside the joint. What happens is that the synovial fluid coats the surface of the joint cartilage, by forming a thin layer over it. However, most types of arthritis have similar early symptoms– joint pain, stiffness and swelling.The synovial fluid is actually secreted by the synovial membrane, which coats the interior of the synovial joints. For example in osteoarthritis, the cartilage becomes worn, and in rheumatoid arthritis the body’s immune system attacks the synovial membrane. There are more than 100 different types of arthritis, arising from problems in different parts of the joint. Synovial joints may also become inflamed, called arthritis. The moving parts in synovial joints make them particularly vulnerable to injury, most commonly sprains, where ligaments become stretched or torn, and dislocations. synovial membrane (or synovium) – a special layer of cells that lines the joint capsule and produces the synovial fluid.synovial fluid – a clear sticky substance that fills the synovial cavity and nourishes and lubricates the cartilage surfaces as they move against each other, like oil lubricating a piston.Together with the ligaments, tendons and muscles, the capsule keeps the bones of the joint in place. joint capsule – a fibrous material that encloses the joint.This acts as a shock absorber and reduces friction as the bones move over each other. cartilage – a smooth gristly material that covers the surface of the bones.
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